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過去の星野賞受賞者

◆星野賞受賞者

 
第1回西 徹Differential expression of two types of the neurofibromatosis type 1(NF1) gene transcripts related to neuronal differentiation. Oncogene 6:1555-1559, 1991
第2回山崎 俊樹Role of histocompatibility antigen gene and protooncogene expressions in intracerebral tumorigenicity of mouse neuroblastoma. J Neurosurg 78:619-629, 1993
第3回浅井 昭雄The s-Myc protein having the ability to induce apoptosis is selectively cxpressed in rat embryo chondrocytes. Oncogene 9:2345-2352, 1994
第4回近藤 精二Interleukin-1beta-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells, Cancer Res 55:6166-6171, 1995
第5回泉本 修一Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion. Cancer Res 56:1440-1444,1996
第6回植木 敬介CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res 56:150-153, 1996
第7回永根 基雄Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bc1-XL and caspase-3-like proteases. Proc Natl Acad Sci, USA 95:5724-5729, 1998
第8回篠浦 伸禎Highly augmented cytopathic effect of a fiber-mutant E1B-defective adenovirus for gene therapy of gliomas. Cancer Res 59:3411-3416, 1999
第9回池田 圭朗Complement depletioon facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simples viru mutant. J Virology 74:4765-4775, 2000
三島 一彦A peptide derived from the non-receptor-binding region of urokinase plasminogen activator inhibits glioblastoma growth and angiogenesis in vivo in combination with cisplatin. Proc Natl Acad Sci,USA 97:8484-8489, 2000
第10回園田 順彦Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma. Cancer Res 61:4956-4960, 2001
第11回石内 勝吾Blockage of Ca2+-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells. Nature Medicine 8:971-978, 2002
第12回岡田 義文Selection pressures of TP53 mutation and microenvironmental location influence epidermal growth factor receptor gene amplification in human glioblastomas. Cancer Res 63:413-416, 2003
第13回中田 光俊The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells. Cancer Research 64;3179-3185, 2004.
第14回該当者なし 
第15回木下 学Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc Natl Acad Sci 103:11719-11723, 2006
第16回該当者なし 
第17回黒住 和彦Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy. J Natl Cancer Inst 99:1768-1781, 2007
第18回丸本 朋稔Development of a novel mouse glioma model using lentiviral vectors. Nat Med 15:110-116, 2009
第19回武笠 晃丈Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence. Proceedings of the National Academy of Sciences of the United States of America107; 2616-2621,2010.
第20回夏目 敦至Girdin maintains the stemness of glioblastoma stem cells. Oncogene 31, 2715-2714, 2012.
第21回有田 英之Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss. Acta Neuropathologica,126,267-276,2013
第22回佐藤 篤Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK. Stem Cell Translational Medicine 1; 811-824, 2012
第23回小澤 達也Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma.. Cancer cell 26: 288-300, 2014
鈴木 啓道Mutational landscape and clonal architecture in grade II and III gliomas. Nat Genet. 47: 458-468, 2015
第24回立石 健祐 Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.Cancer Cell 28; 773-784, 2015
第25回大場 茂生 Mutant IDH1 Exuression Drives TERI Promoter Reactivation as Part of the Cellular Transformation Process. Cancer Res;76(22);6680-9, 2016
第26回木島 教行 A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell 172:1050–1062, 2018
第27回 寺田 行範 Human Pluripotent Stem Cell-Derived Tumor Model Uncovers the Embryonic Stem Cell Signature as a Key Driver in Atypical Teratoid/Rhabdoid Tumor. Cell Reports 26, 2608-2621, Mar 5, 2019
第28回 甲賀 智之 Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells. Nature Communications (2020) 11(1):550. doi.org/10.1038/s41467-020-14312- 1
髙見 浩数 Integrated clinical, histopathological, and molecular data analysis of 190 central nervous system germ cell tumors from the iGCT Consortium. Neuro Oncol 21(12):1565-1577, 2019
第29回 北村 洋平 Anti-EGFR VHH-armed death receptor ligand-engineered allogeneic stem cells have therapeutic efficacy in diverse brain metastatic breast cancers. Science Advances (2021) 7(10):eabe8671.
第30回 藤本 健二 TERT promoter mutation status is necessary and sufficient to diagnose IDH-wildtype diffuse astrocytic glioma with molecular features of glioblastoma. Acta Neuropathol 2021 Aug;142(2):323-338.
第31回 中田 聡 Epigenetic upregulation of Schlafen11 renders WNT- and SHH-activated medulloblastomas sensitive to cisplatin. Neuro Oncol. 2023 May 4;25(5):899-912.
第32回 野村 昌志 Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma. Cancer Cell 42, 1–11, May 13, 2024

◆第32回星野賞授賞式